Varaico: Literature-Extracted Genetic Variants

Gene:XPA
Variant:p.K222E
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XPA

NM_000380.4:p.K222E

Associated Papers

A key interaction with RPA orients XPA in NER complexes.

Topolska-Woś AM et al.

Nucleic Acids Research, 2020

Investigation of the probable homo-dimer model of the Xeroderma pigmentosum complementation group A (XPA) protein to represent the DNA-binding core.

Pradhan S et al.

Journal of Biomolecular Structure & Dynamics, 2019

Structural characterization of the redefined DNA-binding domain of human XPA.

Lian FM et al.

Biochemical and Biophysical Research Communications, 2019

Analysis of DNA binding by human factor xeroderma pigmentosum complementation group A (XPA) provides insight into its interactions with nucleotide excision repair substrates.

Sugitani N et al.

The Journal of Biological Chemistry, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."