Varaico: Literature-Extracted Genetic Variants

Gene:XRCC1
Variant:p.T523A
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XRCC1

NM_006297.3:p.T523A

Associated Papers

Species variations in XRCC1 recruitment strategies for FHA domain-containing proteins.

London RE

Dna Repair, 2022

XRCC1 phosphorylation affects aprataxin recruitment and DNA deadenylation activity.

Horton JK et al.

Dna Repair, 2018

XRCC1-mediated repair of strand breaks independent of PNKP binding.

Horton JK et al.

Dna Repair, 2017

The Rev1 interacting region (RIR) motif in the scaffold protein XRCC1 mediates a low-affinity interaction with polynucleotide kinase/phosphatase (PNKP) during DNA single-strand break repair.

Breslin C et al.

The Journal of Biological Chemistry, 2017

SSRP1 Cooperates with PARP and XRCC1 to Facilitate Single-Strand DNA Break Repair by Chromatin Priming.

Gao Y et al.

Cancer Research, 2017

Damage response of XRCC1 at sites of DNA single strand breaks is regulated by phosphorylation and ubiquitylation after degradation of poly(ADP-ribose).

Wei L et al.

Journal of Cell Science, 2013

Tidying up loose ends: the role of polynucleotide kinase/phosphatase in DNA strand break repair.

Weinfeld M et al.

Trends in Biochemical Sciences, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."