Varaico: Literature-Extracted Genetic Variants

Gene:XRCC1
Variant:p.L360R
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XRCC1

NM_006297.3:p.L360R

Associated Papers

PML-like subnuclear bodies, containing XRCC1, juxtaposed to DNA replication-based single-strand breaks.

Kordon MM et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2019

Base excision repair defects invoke hypersensitivity to PARP inhibition.

Horton JK et al.

Molecular Cancer Research : Mcr, 2014

Strategic Combination of DNA-Damaging Agent and PARP Inhibitor Results in Enhanced Cytotoxicity.

Horton JK et al.

Frontiers in Oncology, 2013

Mouse models of XRCC1 DNA repair polymorphisms and cancer.

Ladiges WC

Oncogene, 2006

Independent roles of XRCC1's two BRCT motifs in recovery from methylation damage.

Kubota Y et al.

Dna Repair, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."