Associated Papers
Molecular dynamics simulations reveal R399Q mutation disrupts XRCC1-polβ interaction, potentially impairing DNA base excision repair pathway.
Goswami N et al.
Journal of Biomolecular Structure & Dynamics, 2025
Impact of DNA ligase 1 and IIIα interactions with APE1 and polβ on the efficiency of base excision repair pathway at the downstream steps.
Almohdar D et al.
The Journal of Biological Chemistry, 2024
Impact of polβ/XRCC1 Interaction Variants on the Efficiency of Nick Sealing by DNA Ligase IIIα in the Base Excision Repair Pathway.
Almohdar D et al.
Journal of Molecular Biology, 2024
Genetic polymorphisms in DNA repair genes and hepatocellular carcinoma risk.
Ghaderi-Zefrehi H et al.
Dna Repair, 2021
The scaffold protein XRCC1 stabilizes the formation of polβ/gap DNA and ligase IIIα/nick DNA complexes in base excision repair.
Tang Q et al.
The Journal of Biological Chemistry, 2021
Association between Single Nucleotide Polymorphisms and Glioma Risk: A Systematic Literature Review.
Tavares CB et al.
Cancer Investigation, 2020
The influence of XRCC1 genetic variants on lung cancer susceptibility in Chinese Han population.
Wang Y et al.
Gene, 2015
Association between X-ray repair cross-complementing group 1 gene polymorphisms and glioma risk: a systematic review and meta-analysis based on 22 case-control studies.
Li J et al.
International Journal of Clinical and Experimental Medicine, 2015
Glioma risks associate with genetic polymorphisms of XRCC1 gene in Chinese population.
Feng X et al.
Journal of Cellular Biochemistry, 2014
Genetic polymorphisms of XRCC1 gene and susceptibility to hepatocellular carcinoma in Chinese population.
Jiang T et al.
Medical Oncology (northwood, London, England), 2014
Potentially functional SNPs (pfSNPs) as novel genomic predictors of 5-FU response in metastatic colorectal cancer patients.
Wang J et al.
Plos One, 2014
Variation in base excision repair capacity.
Wilson DM et al.
Mutation Research, 2011
Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population.
Berquist BR et al.
Nucleic Acids Research, 2010
Nonsynonymous single nucleotide polymorphisms in DNA damage repair pathways and lung cancer risk.
Tanaka Y et al.
Cancer, 2010
[Study on polymorphisms in metabolic enzyme genes, DNA repair genes and individual susceptibility to hepatocellular carcinoma].
Ye XP et al.
Wei Sheng Yan Jiu = Journal of Hygiene Research, 2006
Mouse models of XRCC1 DNA repair polymorphisms and cancer.
Ladiges WC
Oncogene, 2006
Identifying functional genetic variants in DNA repair pathway using protein conservation analysis.
Savas S et al.
Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2004