Varaico: Literature-Extracted Genetic Variants

Gene:XRCC3
Variant:p.R81C
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XRCC3

NM_005432.4:p.R81C

Associated Papers

Research on the effects of rs1800566 C/T polymorphism of NAD(P)H quinone oxidoreductase 1 gene on cancer risk involves analysis of 43,736 cancer cases and 56,173 controls.

Zhou H et al.

Frontiers in Oncology, 2022

36338728 (PubMed )
Supplement: Table_1.docx

Association between Single Nucleotide Polymorphisms and Glioma Risk: A Systematic Literature Review.

Tavares CB et al.

Cancer Investigation, 2020

Genetic variation in the DNA repair pathway as a potential determinant of response to platinum-based chemotherapy in breast cancer.

Beheshti F et al.

Journal of Cellular Physiology, 2018

Genetic Predisposition to Cervical Cancer and the Association With XRCC1 and TGFB1 Polymorphisms.

Al-Harbi NM et al.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, 2017

Association between the DNA Repair Gene XRCC3 rs861539 Polymorphism and Risk of Osteosarcoma: a Systematic Review and Meta-Analysis

Sobhan MR et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

Association between x-ray repair cross-complementing group 3 (XRCC3) genetic polymorphisms and papillary thyroid cancer susceptibility in a Chinese Han population.

Yuan K et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

[Relationship between RAD51-G135C and XRCC3-C241T Single Nucleotide Polymorphisms and Onset of Acute Myeloid Leukemia].

Miao L et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2015

Germline TYMS genotype is highly predictive in patients with metastatic gastrointestinal malignancies receiving capecitabine-based chemotherapy.

Joerger M et al.

Cancer Chemotherapy and Pharmacology, 2015

Genetic susceptibility to arsenic-induced skin lesions and health effects: a review.

Paul S et al.

Genes and Environment : the Official Journal of the Japanese Environmental Mutagen Society, 2015

Genetic polymorphisms of RAD51 and XRCC3 and acute myeloid leukemia risk: a meta-analysis.

Li C et al.

Leukemia & Lymphoma, 2014

Comprehensive assessment of the association between DNA repair gene XRCC3 Thr241Met polymorphism and leukemia risk.

Qin L et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Significant associations between X-ray repair cross-complementing group 3 genetic polymorphisms and thyroid cancer risk.

Yu XL et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Quantitative assessment of the associations between DNA repair gene XRCC3 Thr241Met polymorphism and gastric cancer.

Wang Z et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Association between the XRCC3 Thr241Met polymorphism and cervical cancer risk: a meta-analysis.

Qin LY et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2014

Haplotype analyses of DNA repair gene polymorphisms and their role in ulcerative colitis.

Bardia A et al.

Plos One, 2014

Significant association between XRCC3 C241T polymorphism and increased risk of hepatocellular carcinoma: a meta-analysis.

Wu D et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

Association between the XRCC3 C241T polymorphism and lung cancer risk in the Asian population.

Tian X et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

DNA repair gene XRCC3 Thr241Met polymorphism and hepatocellular carcinoma risk.

Duan C et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

SNPs in genes implicated in radiation response are associated with radiotoxicity and evoke roles as predictive and prognostic biomarkers.

Alsbeih G et al.

Radiation Oncology (london, England), 2013

HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia.

Alsbeih G et al.

Infectious Agents and Cancer, 2013

Polymorphisms in DNA repair genes and susceptibility to glioma in a chinese population.

Pan WR et al.

International Journal of Molecular Sciences, 2013

Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

Joerger M et al.

Cancer, 2012

Association of XRCC3 and XPD751 SNP with efficacy of platinum-based chemotherapy in advanced NSCLC patients.

Chen X et al.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2012

Involvement of single-nucleotide polymorphisms in predisposition to head and neck cancer in Saudi Arabia.

Al-Hadyan KS et al.

Genetic Testing and Molecular Biomarkers, 2012

[Relationship between RAD51-g135C and XRCC3-C241T polymorphisms and prognosis of inv (16)/ t(16;16) (CBFbeta-MYH11) acute myeloid leukemia].

Liu L et al.

Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi, 2011

Detoxification and DNA repair genes polymorphisms and susceptibility of primary myelodysplastic syndromes in Chinese population.

Li L et al.

Leukemia Research, 2011

[Relationship between RAD51-G135C/XRCC3-C241T polymorphisms and development of acute myeloid leukemia with recurrent chromosome translocation].

Yang L et al.

Zhonghua Xue Ye Xue Za Zhi = Zhonghua Xueyexue Zazhi, 2011

DNA repair genes XRCC1 and XRCC3 polymorphisms and their relationship with the level of micronuclei in breast cancer patients.

Santos RA et al.

Genetics and Molecular Biology, 2010

Association between normal tissue complications after radiotherapy and polymorphic variations in TGFB1 and XRCC1 genes.

Alsbeih G et al.

Radiation Research, 2010

Association of polymorphisms in proinflammatory cytokine genes with the development of oral cancer in Southern Thailand.

Kietthubthew S et al.

International Journal of Hygiene and Environmental Health, 2010

[Relationship between NQO1C(609T), RAD51(G135C), XRCC3(C241T) single nucleotide polymorphisms and acute lymphoblastic leukemia].

Zhang ZQ et al.

Zhongguo Shi Yan Xue Ye Xue Za Zhi, 2009

Double-strand break DNA repair genotype predictive of later mortality and cancer incidence in a cohort of non-smokers.

Neasham D et al.

Dna Repair, 2009

Association between XRCC1 G399A Polymorphism and Late Complications to Radiotherapy in Saudi Head and Neck Cancer Patients.

Alsbeih GA et al.

Journal of the Egyptian National Cancer Institute, 2008

Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy.

Ruzzo A et al.

The Pharmacogenomics Journal, 2008

[Polymorphisms of RAD51(G135C) and XRCC3(C241T) genes and correlations thereof with prognosis and clinical outcomes of acute myeloid leukemia].

Liu L et al.

Zhonghua Yi Xue Za Zhi, 2008

DNA repair polymorphisms and outcome of chemotherapy for acute myelogenous leukemia: a report from the Children's Oncology Group.

Bhatla D et al.

Leukemia, 2008

DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy.

Andrew AS et al.

Human Heredity, 2008

Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies.

Guillem VM et al.

Leukemia, 2007

Radiosensitivity of human fibroblasts is associated with amino acid substitution variants in susceptible genes and correlates with the number of risk alleles.

Alsbeih G et al.

International Journal of Radiation Oncology, Biology, Physics, 2007

Polymorphisms in genes involved in DNA repair and metabolism of xenobiotics in individual susceptibility to sporadic diffuse gastric cancer.

Ruzzo A et al.

Clinical Chemistry and Laboratory Medicine, 2007

[Genetic polymorphisms in X-ray repair cross-complementing gene 1 and susceptibility to papillary thyroid carcinoma].

Zhu QX et al.

Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 2004

Genetic polymorphisms of DNA repair and xenobiotic-metabolizing enzymes: role in mutagen sensitivity.

Tuimala J et al.

Carcinogenesis, 2002

Gemcitabine and platinum pathway pharmacogenetics in Asian breast cancer patients.

Wong AL et al.

Cancer Genomics & Proteomics, 0

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