Varaico: Literature-Extracted Genetic Variants

Gene:XRN1
Variant:p.D208A
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XRN1

NM_001282857.2:p.D208A

Associated Papers

Proper 5'-3' cotranslational mRNA decay in yeast requires import of Xrn1 to the nucleus.

Jordán-Pla A et al.

Plos One, 2025

Evidence that Xrn1 is in complex with Gcn1, and is required for full levels of eIF2α phosphorylation.

Shanmugam R et al.

The Biochemical Journal, 2024

The exonuclease Xrn1 activates transcription and translation of mRNAs encoding membrane proteins.

Blasco-Moreno B et al.

Nature Communications, 2019

Posttranscriptional regulation of the karyogamy gene by Kem1p/Xrn1p exoribonuclease and Rok1p RNA helicase of Saccharomyces cerevisiae.

Kim J et al.

Biochemical and Biophysical Research Communications, 2004

The yeast ubiquitin protease, Ubp3p, promotes protein stability.

Brew CT et al.

Genetics, 2002

Active-site mutations in the Xrn1p exoribonuclease of Saccharomyces cerevisiae reveal a specific role in meiosis.

Solinger JA et al.

Molecular and Cellular Biology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."