Varaico: Literature-Extracted Genetic Variants

Gene:YAP1
Variant:p.S94A
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YAP1

NM_001130145.3:p.S94A

Associated Papers

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction-Associated Steatotic Liver Disease.

Lee NY et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2026

C-terminal fusion partner activity contributes to the oncogenic functions of YAP1::TFE3.

Cimino PJ et al.

Scientific Reports, 2025

YAP maintains the dynamics of TDP-43 condensates and antagonizes TDP-43 pathological aggregates.

Zhang J et al.

Nature Cell Biology, 2025

C-terminal fusion partner activity contributes to the oncogenic functions of YAP1::TFE3.

Cimino PJ et al.

Biorxiv : the Preprint Server for Biology, 2025

PDE4D drives rewiring of the MAPK pathway in BRAF-mutated melanoma resistant to MAPK inhibitors.

Delyon J et al.

Cell Communication and Signaling : Ccs, 2024

Aggressive high-grade NF2 mutant meningiomas downregulate oncogenic YAP signaling via the upregulation of VGLL4 and FAT3/4.

Parrish AG et al.

Biorxiv : the Preprint Server for Biology, 2024

The AMPK-Sirtuin 1-YAP axis is regulated by fluid flow intensity and controls autophagy flux in kidney epithelial cells.

Claude-Taupin A et al.

Nature Communications, 2023

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis.

Wu Z et al.

Nature Communications, 2023

Reduced YAP1 and FOLR1 in gliomas predict better response to chemotherapeutics.

Patrick S et al.

Cellular Signalling, 2023

Transforming Growth Factor Beta Promotes Inflammation and Tumorigenesis in Smad4-Deficient Intestinal Epithelium in a YAP-Dependent Manner.

Liu L et al.

Advanced Science (weinheim, Baden-wurttemberg, Germany), 2023

Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors.

Garcia-Rendueles MER et al.

Molecular Cancer, 2022

Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice.

Szulzewsky F et al.

Genes & Development, 2022

36008139 (PubMed )
Supplement: supp_gad.349876.122_Supplemental_Data.pdf

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

Dieter SM et al.

Oncogene, 2022

RhoA-ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic-like flow.

Mohammadalipour A et al.

Faseb Bioadvances, 2022

YAP1-mediated regulation of mitochondrial dynamics in IDH1 mutant gliomas.

Patrick S et al.

Journal of Cell Science, 2021

UDP-glucose pyrophosphorylase 2, a regulator of glycogen synthesis and glycosylation, is critical for pancreatic cancer growth.

Wolfe AL et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis.

Szulzewsky F et al.

Genes & Development, 2020

RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer.

Qiao Y et al.

Oncogene, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."