Associated Papers
Transcriptomic profiling of insulinomas reveals a new "low-endocrine" subtype with low YY1 expressions.
Li Y et al.
Pancreatology : Official Journal of the International Association of Pancreatology (iap) ... [et Al.], 2026
Unstructured but critical: The role of YY1 and YY2 disorder in promoter recognition networks, transcriptional control, and oncogenesis.
Figiel M et al.
Biochimica Et Biophysica Acta. Reviews on Cancer, 2025
Molecular Classification and Characterization of Noninsulinoma: Ready for Prime Time in Clinical Practice?
Zhang K
International Journal of Surgical Pathology, 2025
Pancreatic neuroendocrine neoplasms (pNENs): Genetic and environmental biomarkers for risk of occurrence and prognosis.
Tacelli M et al.
Seminars in Cancer Biology, 2025
Clinical Relevance of ATRX/DAXX Gene Mutations and ALT in Functioning Pancreatic Neuroendocrine Tumors.
van T Veld BR et al.
Endocrine Pathology, 2025
Molecular Basis of Pancreatic Neuroendocrine Tumors.
Maluchenko A et al.
International Journal of Molecular Sciences, 2024
Implications of noncoding regulatory functions in the development of insulinomas.
Ramos-Rodríguez M et al.
Cell Genomics, 2024
Metastatic insulinoma: exploration from clinicopathological signatures and genetic characteristics.
Zhang J et al.
Frontiers in Oncology, 2023
Molecular biology of pancreatic neuroendocrine tumors: From mechanism to translation.
Shen X et al.
Frontiers in Oncology, 2022
Mutation Status in Phosphatase and Tensin Homolog Deleted on Chromosome 10 Gene in X-ray-Induced Insulinoma Cell Line Rin-5F.
Kiba T et al.
Pancreas, 2021
A 9-month-old Chinese patient with Gabriele-de Vries syndrome due to novel germline mutation in the YY1 gene.
Tan L et al.
Molecular Genetics & Genomic Medicine, 2021
New Regions With Molecular Alterations in a Rare Case of Insulinomatosis: Case Report With Literature Review.
Anoshkin K et al.
Frontiers in Endocrinology, 2021
Cystic Fibrosis-Related Pancreatic Cysts Decrease in Size and Number Upon Treatment With Cystic Fibrosis Transmembrane Conductance Regulator Modulators.
de Vries JM et al.
Pancreas, 2020
Genetic and epigenetic alterations in pancreatic neuroendocrine tumors.
Tirosh A et al.
Journal of Gastrointestinal Oncology, 2020
Whole-genome sequencing reveals distinct genetic bases for insulinomas and non-functional pancreatic neuroendocrine tumours: leading to a new classification system.
Hong X et al.
Gut, 2020
EM-mosaic detects mosaic point mutations that contribute to congenital heart disease.
Hsieh A et al.
Genome Medicine, 2020
The effect of D380Y pathogenic mutation in human Yin Yang 1 on the protein's structure and function.
Figiel M et al.
Acta Biochimica Polonica, 2020
Yin Yang 1 promotes the Warburg effect and tumorigenesis via glucose transporter GLUT3.
Wang Y et al.
Cancer Science, 2018
Frequency and consequence of the recurrent YY1 p.T372R mutation in sporadic insulinomas.
Parekh VI et al.
Endocrine-related Cancer, 2018
Recurrent loss of heterozygosity correlates with clinical outcome in pancreatic neuroendocrine cancer.
Lawrence B et al.
Npj Genomic Medicine, 2018
Insights into beta cell regeneration for diabetes via integration of molecular landscapes in human insulinomas.
Wang H et al.
Nature Communications, 2017
Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management.
Challis BG et al.
Endocrine Connections, 2017
Genetic and epigenetic drivers of neuroendocrine tumours (NET).
Di Domenico A et al.
Endocrine-related Cancer, 2017
T372R Mutation Status in Yin Yang 1 Gene in Insulinoma Patients.
Irshad K et al.
Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 2017
Neomorphic mutations create therapeutic challenges in cancer.
Takiar V et al.
Oncogene, 2017
Identification of rare paired box 3 variant in strabismus by whole exome sequencing.
Gong HM et al.
International Journal of Ophthalmology, 2017
GEP- NETS UPDATE: Genetics of neuroendocrine tumors.
Crona J et al.
European Journal of Endocrinology, 2016
Significance of the pathogenic mutation T372R in the Yin Yang 1 protein interaction with DNA--thermodynamic studies.
Nieborak A et al.
Febs Letters, 2016
Frequency and clinical correlates of somatic Ying Yang 1 mutations in sporadic insulinomas.
Lichtenauer UD et al.
The Journal of Clinical Endocrinology and Metabolism, 2015
Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas.
Cromer MK et al.
Proceedings of the National Academy of Sciences of the United States of America, 2015
Decoding the Molecular and Mutational Ambiguities of Gastroenteropancreatic Neuroendocrine Neoplasm Pathobiology.
Kidd M et al.
Cellular and Molecular Gastroenterology and Hepatology, 2015
Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors.
Modali SD et al.
Molecular Endocrinology (baltimore, Md.), 2015
Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours.
Jiang X et al.
Nature Communications, 2014
Neuroendocrine cancer: Insulinomas-recurrent mutations identified in YY1.
Greenhill C
Nature Reviews. Endocrinology, 2014
Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1.
Cao Y et al.
Nature Communications, 2013
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension.
Choi M et al.
Science (new York, N.y.), 2011
Exome-level comparison of primary well-differentiated neuroendocrine tumors and their cell lines.
Boora GK et al.
Cancer Genetics, 0