Associated Papers
Positive feedback between the T cell kinase Zap70 and its substrate LAT acts as a clustering-dependent signaling switch.
Dine E et al.
Cell Reports, 2021
34161759 (PubMed )
Supplement: NIHMS1717852-supplement-8.pdf
A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity.
Hsu LY et al.
The Journal of Experimental Medicine, 2009
Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells.
Simon M et al.
The Journal of Biological Chemistry, 2005
Tyrosine 315 determines optimal recruitment of ZAP-70 to the T cell antigen receptor.
Di Bartolo V et al.
European Journal of Immunology, 2002
T cell development and T cell responses in mice with mutations affecting tyrosines 292 or 315 of the ZAP-70 protein tyrosine kinase.
Magnan A et al.
The Journal of Experimental Medicine, 2001
Role of the Src homology 2 domains and interdomain regions in ZAP-70 phosphorylation and enzymatic activity.
Magistrelli G et al.
European Journal of Biochemistry, 1999
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