Associated Papers
The endonuclease activity of MCPIP1 controls the neoplastic transformation of epithelial cells via the c-Met/CD44 axis.
Marona P et al.
Cell Communication and Signaling : Ccs, 2025
Regnase-1 D141N mutation induces CD4+ T cell-mediated lung granuloma formation via upregulation of Pim2.
Htun TS et al.
International Immunology, 2024
Regulation of lymphoid-myeloid lineage bias through regnase-1/3-mediated control of Nfkbiz.
Uehata T et al.
Blood, 2024
Breaking self-regulation of Regnase-1 promotes its own protein expression.
Piboonprai K et al.
Genes to Cells : Devoted to Molecular & Cellular Mechanisms, 2023
Resistance to tyrosine kinase inhibitors promotes renal cancer progression through MCPIP1 tumor-suppressor downregulation and c-Met activation.
Marona P et al.
Cell Death & Disease, 2022
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
Behrens G et al.
Nature Immunology, 2021
Accelerated FASTK mRNA degradation induced by oxidative stress is responsible for the destroyed myocardial mitochondrial gene expression and respiratory function in alcoholic cardiomyopathy.
Zhang F et al.
Redox Biology, 2021
Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor.
Tamir TY et al.
Journal of Cell Science, 2020
Substrate specificity of human MCPIP1 endoribonuclease.
Wilamowski M et al.
Scientific Reports, 2018
RNA sequencing reveals widespread transcriptome changes in a renal carcinoma cell line.
Lichawska-Cieslar A et al.
Oncotarget, 2018
Regnase-1 and Roquin Nonredundantly Regulate Th1 Differentiation Causing Cardiac Inflammation and Fibrosis.
Cui X et al.
Journal of Immunology (baltimore, Md. : 1950), 2017
Regnase-1 Maintains Iron Homeostasis via the Degradation of Transferrin Receptor 1 and Prolyl-Hydroxylase-Domain-Containing Protein 3 mRNAs.
Yoshinaga M et al.
Cell Reports, 2017
Rae1/YacP, a new endoribonuclease involved in ribosome-dependent mRNA decay in Bacillus subtilis.
Leroy M et al.
The Embo Journal, 2017
Immune Regulator MCPIP1 Modulates TET Expression during Early Neocortical Development.
Jiang H et al.
Stem Cell Reports, 2016
MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.
Garg AV et al.
Immunity, 2015
Regnase-1, a ribonuclease involved in the regulation of immune responses.
Akira S
Cold Spring Harbor Symposia on Quantitative Biology, 2013
Structural study of MCPIP1 N-terminal conserved domain reveals a PIN-like RNase.
Xu J et al.
Nucleic Acids Research, 2012