Varaico: Literature-Extracted Genetic Variants

Gene:ZDHHC3
Variant:p.C157S
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ZDHHC3

NM_001135179.2:p.C157S

Associated Papers

Palmitoyl-transferase 3 promotes mitochondrial antiviral signaling protein degradation by modulating its ubiquitination.

Yi L et al.

International Journal of Biological Macromolecules, 2025

S-acylation of NLRP3 provides a nigericin sensitive gating mechanism that controls access to the Golgi.

Williams DM et al.

Elife, 2024

Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice.

Ni H et al.

Nature Communications, 2024

NPC1 regulates the distribution of phosphatidylinositol 4-kinases at Golgi and lysosomal membranes.

Kutchukian C et al.

The Embo Journal, 2021

Binding of Herpes Simplex Virus 1 UL20 to GODZ (DHHC3) Affects Its Palmitoylation and Is Essential for Infectivity and Proper Targeting and Localization of UL20 and Glycoprotein K.

Wang S et al.

Journal of Virology, 2017

Activation of STING requires palmitoylation at the Golgi.

Mukai K et al.

Nature Communications, 2016

27324217 (PubMed )
Supplement: ncomms11932-s1.pdf

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.

Oku S et al.

The Journal of Biological Chemistry, 2013

Regulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cells.

Oh Y et al.

Cell Death and Differentiation, 2012

Golgi-specific DHHC zinc finger protein GODZ mediates membrane Ca2+ transport.

Hines RM et al.

The Journal of Biological Chemistry, 2010

GODZ-mediated palmitoylation of GABA(A) receptors is required for normal assembly and function of GABAergic inhibitory synapses.

Fang C et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."