Varaico: Literature-Extracted Genetic Variants

Gene:ZFHX3
Variant:p.E2677K
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ZFHX3

NM_006885.4:p.E2677K

Associated Papers

A case of microsatellite instability-high clinically advanced castration-resistant prostate cancer showing a remarkable response to pembrolizumab sustained over at least 18 months.

Shimizu K et al.

Cold Spring Harbor Molecular Case Studies, 2022

35487690 (PubMed )
Supplement: supp_mcs.a006194_Supplemental_Table_S1.xlsx › merge_mutation_filt.target

Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

Temko D et al.

The Journal of Pathology, 2018

29604063 (PubMed )
Supplement: PATH-245-283-s021.xlsx › EC.Drivers.Edited
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."