Varaico: Literature-Extracted Genetic Variants

Gene:ZFP36
Variant:p.C124R
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ZFP36

NM_003407.5:p.C124R

Associated Papers

Structural basis for the recruitment of the human CCR4-NOT deadenylase complex by tristetraprolin.

Fabian MR et al.

Nature Structural & Molecular Biology, 2013

23644599 (PubMed )
Supplement: NIHMS767724-supplement-Supplemental_online_methods.pdf

UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression.

Al-Saif M et al.

Molecular Therapy : the Journal of the American Society of Gene Therapy, 2012

Direct binding of specific AUF1 isoforms to tandem zinc finger domains of tristetraprolin (TTP) family proteins.

Kedar VP et al.

The Journal of Biological Chemistry, 2012

Interactions of CCCH zinc finger proteins with mRNA: non-binding tristetraprolin mutants exert an inhibitory effect on degradation of AU-rich element-containing mRNAs.

Lai WS et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."