Associated Papers
Systematized reporter assays reveal ZIC protein regulatory abilities are Subclass-specific and dependent upon transcription factor binding site context.
Ahmed JN et al.
Scientific Reports, 2020
A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.
Dykes IM et al.
Scientific Reports, 2018
Zic2 mutation causes holoprosencephaly via disruption of NODAL signalling.
Houtmeyers R et al.
Human Molecular Genetics, 2016
Transcription factor Zic2 inhibits Wnt/β-catenin protein signaling.
Pourebrahim R et al.
The Journal of Biological Chemistry, 2011
In vitro analysis of partial loss-of-function ZIC2 mutations in holoprosencephaly: alanine tract expansion modulates DNA binding and transactivation.
Brown L et al.
Human Molecular Genetics, 2005
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