Varaico: Literature-Extracted Genetic Variants

Gene:ZP1
Variant:p.V570M
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ZP1

NM_207341.4:p.V570M

Associated Papers

Genetic landscape of human oocyte/embryo defects.

Chen B et al.

Cell Genomics, 2026

41005306 (PubMed )
Supplement: mmc3.xlsx › Table_S2

Abnormal zona pellucida and follicular development in ZP1-mutant macaques.

Meng W et al.

Zoological Research, 2025

Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucida.

Zhang X et al.

Journal of Ovarian Research, 2024

ZP1-Y262C mutation causes abnormal zona pellucida formation and female infertility in humans.

Cao G et al.

Frontiers in Genetics, 2024

Zona Pellucida Genes and Proteins: Essential Players in Mammalian Oogenesis and Fertility.

Wassarman PM et al.

Genes, 2021

Molecular genetics of infertility: loss-of-function mutations in humans and corresponding knockout/mutated mice.

Jiao SY et al.

Human Reproduction Update, 2021

Human Zona Pellucida Glycoproteins: Binding Characteristics With Human Spermatozoa and Induction of Acrosome Reaction.

Gupta SK

Frontiers in Cell and Developmental Biology, 2021

Novel biallelic loss-of-function variants in ZP1 identified in an infertile female with empty follicle syndrome.

Liu M et al.

Journal of Assisted Reproduction and Genetics, 2020

Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.

Cao Q et al.

Journal of Cellular and Molecular Medicine, 2020

A novel homozygous nonsense ZP1 variant causes human female infertility associated with empty follicle syndrome (EFS).

Xu Q et al.

Molecular Genetics & Genomic Medicine, 2020

Homozygous Splice Site Mutation in ZP1 Causes Familial Oocyte Maturation Defect.

Okutman Ö et al.

Genes, 2020

Zona pellucida genes and proteins and human fertility.

Litscher ES et al.

Trends in Developmental Biology, 2020

Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation.

Zhou Z et al.

Human Genetics, 2019

[The human zona pellucida: New genetic findings].

Trocka D et al.

Medecine Sciences : M/s, 0

Genetic variations in zona pellucida glycoproteins: Implications for fertility and ART outcomes.

Rajput N et al.

Mutation Research. Reviews in Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."