Varaico: Literature-Extracted Genetic Variants

Gene:ZP2
Variant:p.C372S
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ZP2

NM_001376232.1:p.C372S

Associated Papers

Genetic landscape of human oocyte/embryo defects.

Chen B et al.

Cell Genomics, 2026

41005306 (PubMed )
Supplement: mmc3.xlsx › Table_S2

Advances in monogenic female infertility.

Gu H et al.

Journal of Genetics and Genomics = Yi Chuan Xue Bao, 2025

Single-cell RNA sequencing of human oocytes reveals a differential transcriptomic profile associated with agar-like zona pellucida.

Zhang X et al.

Journal of Ovarian Research, 2024

A heterozygous ZP2 mutation causes zona pellucida defects and female infertility in mouse and human.

Liu SL et al.

Iscience, 2023

Identification of zona pellucida defects revealed a novel loss-of-function mutation in ZP2 in humans and rats.

Zeng J et al.

Frontiers in Endocrinology, 2023

Can successful pregnancy be achieved and predicted from patients with identified ZP mutations? A literature review.

Zhou J et al.

Reproductive Biology and Endocrinology : Rb&e, 2022

Novel Heterozygous Mutations in ZP2 Cause Abnormal Zona Pellucida and Female Infertility.

Hou M et al.

Reproductive Sciences (thousand Oaks, Calif.), 2022

Gene mutations impede oocyte maturation, fertilization, and early embryonic development.

Fei CF et al.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology, 2022

Novel mutations in ZP2 and ZP3 cause female infertility in three patients.

Jia W et al.

Journal of Assisted Reproduction and Genetics, 2022

Identification of a heterozygous variant of ZP2 as a novel cause of empty follicle syndrome in humans and mice.

Shen Y et al.

Human Reproduction (oxford, England), 2022

A novel homozygous variant in ZP2 causes abnormal zona pellucida formation and female infertility.

Sun Y et al.

Journal of Assisted Reproduction and Genetics, 2021

Human Zona Pellucida Glycoproteins: Binding Characteristics With Human Spermatozoa and Induction of Acrosome Reaction.

Gupta SK

Frontiers in Cell and Developmental Biology, 2021

Novel biallelic loss-of-function variants in ZP1 identified in an infertile female with empty follicle syndrome.

Liu M et al.

Journal of Assisted Reproduction and Genetics, 2020

Heterozygous mutations in ZP1 and ZP3 cause formation disorder of ZP and female infertility in human.

Cao Q et al.

Journal of Cellular and Molecular Medicine, 2020

Novel mutations in ZP1, ZP2, and ZP3 cause female infertility due to abnormal zona pellucida formation.

Zhou Z et al.

Human Genetics, 2019

[The human zona pellucida: New genetic findings].

Trocka D et al.

Medecine Sciences : M/s, 0

Genetic variations in zona pellucida glycoproteins: Implications for fertility and ART outcomes.

Rajput N et al.

Mutation Research. Reviews in Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."