Associated Papers
Functional landscape of ubiquitin linkages couples K29-linked ubiquitylation to epigenome integrity.
Arroyo-Gomez J et al.
The Embo Journal, 2025
Trabid patient mutations impede the axonal trafficking of adenomatous polyposis coli to disrupt neurite growth.
Frank D et al.
Elife, 2023
TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation.
Chen YH et al.
Nature Communications, 2023
TRABID overexpression enables synthetic lethality to PARP inhibitor via prolonging 53BP1 retention at double-strand breaks.
Ma J et al.
Nature Communications, 2023
Zranb1-mutant mice display abnormal colonic mucus production and exacerbation of DSS-induced colitis.
Tamura A et al.
Biochemical and Biophysical Research Communications, 2022
K29-linked ubiquitin signaling regulates proteotoxic stress response and cell cycle.
Yu Y et al.
Nature Chemical Biology, 2021
Assembly and specific recognition of k29- and k33-linked polyubiquitin.
Michel MA et al.
Molecular Cell, 2015
HectD1 E3 ligase modifies adenomatous polyposis coli (APC) with polyubiquitin to promote the APC-axin interaction.
Tran H et al.
The Journal of Biological Chemistry, 2013
An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.
Licchesi JD et al.
Nature Structural & Molecular Biology, 2011
Trabid, a new positive regulator of Wnt-induced transcription with preference for binding and cleaving K63-linked ubiquitin chains.
Tran H et al.
Genes & Development, 2008
The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.
Harris LD et al.
The Journal of Biological Chemistry, 0
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