apoptosis associated tyrosine kinase

AATYK

KIAA0641

LMTK1

LMR1

AATYK1

PPP1R77

lemur tyrosine kinase 1

protein phosphatase 1, regulatory subunit 77

Serine/threonine-protein kinase LMTK1

Apoptosis-associated tyrosine kinase

Brain apoptosis-associated tyrosine kinase

CDK5-binding protein

Lemur tyrosine kinase 1

p35-binding protein

p35BP

Protein tyrosine and serine/threonine kinase

The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011].

Varaico: Literature-Extracted Genetic Variants

AATK

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbols