Varaico: Literature-Extracted Genetic Variants

ABL1

1,795 papers

RefSeq Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activit...

Pfam Domains

SH3_1aa 67–113UCSCSH3 domain

SH2aa 127–202UCSCSH2 domain

PK_Tyr_Ser-Thraa 242–493UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1025–1130UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 1, non-receptor tyrosine kinase

HGNC Alias Symbols

JTK7; c-ABL; p150

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005157.6

p.V260L

c.778G>T

Surrounding Variants

4 papers

NM_005157.6

p.V260M

c.778G>A

1 paper

NM_005157.6

p.V260L

c.778G>C

2 papers

NM_005157.6

p.G259G

c.777C>T

3 papers

NM_005157.6

p.V260A

c.779T>C

1 paper

NM_005157.6

p.V260G

c.779T>G

1 paper

NM_005157.6

p.G259D

c.776G>A

2 papers

NM_005157.6

p.G259S

c.775G>A

1 paper

NM_005157.6

p.G259C

c.775G>T

1 paper

NM_005157.6

p.W261*

c.782G>A

6 papers

NM_005157.6

p.E258D

c.774G>C

6 papers

NM_005157.6

p.E258D

c.774G>T

1 paper

NM_005157.6

p.W261L

c.782G>T