Varaico: Literature-Extracted Genetic Variants

ABL1

1,795 papers

RefSeq Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activit...

Pfam Domains

SH3_1aa 67–113UCSCSH3 domain

SH2aa 127–202UCSCSH2 domain

PK_Tyr_Ser-Thraa 242–493UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1025–1130UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 1, non-receptor tyrosine kinase

HGNC Alias Symbols

JTK7; c-ABL; p150

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_005157.6

p.T267A

c.799A>G

Surrounding Variants

1 paper

NM_005157.6

p.T267P

c.799A>C

1 paper

NM_005157.6

p.T267S

c.799A>T

3 papers

NM_005157.6

p.L266P

c.797T>C

1 paper

NM_005157.6

p.V268M

c.802G>A

1 paper

NM_005157.6

p.S265R

c.795C>A

1 paper

NM_005157.6

p.S265R

c.795C>G

4 papers

NM_005157.6

p.V268A

c.803T>C

1 paper

NM_005157.6

p.S265N

c.794G>A

1 paper

NM_005157.6

p.S265R

c.793A>C

1 paper

NM_005157.6

p.S265C

c.793A>T

4 papers

NM_005157.6

p.A269T

c.805G>A

2 papers

NM_007313.3

p.A288V

c.863C>T

NM_005157.6

p.A269V

c.806C>T