Varaico: Literature-Extracted Genetic Variants

ABL1

1,795 papers

RefSeq Summary

This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activit...

Pfam Domains

SH3_1aa 67–113UCSCSH3 domain

SH2aa 127–202UCSCSH2 domain

PK_Tyr_Ser-Thraa 242–493UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1025–1130UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 1, non-receptor tyrosine kinase

HGNC Alias Symbols

JTK7; c-ABL; p150

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005157.6

p.K356R

c.1067A>G

Surrounding Variants

1 paper

NM_005157.6

p.K356E

c.1066A>G

2 papers

NM_005157.6

p.K357delFs

c.1069delA

1 paper

NM_005157.6

p.E355D

c.1065G>C

1 paper

NM_005157.6

p.E355D

c.1065G>T

12 papers

NM_005157.6

p.E355A

c.1064A>C

1 paper

NM_005157.6

p.K357T

c.1070A>C

86 papers

NM_005157.6

p.E355G

c.1064A>G

1 paper

NM_005157.6

p.K357_I360Fs

c.1069_1080delinsAGGGTFs

1 paper

NM_005157.6

p.K357N

c.1071A>C

1 paper

NM_005157.6

p.K357N

c.1071A>T

1 paper

NM_005157.6

p.E355Q

c.1063G>C

1 paper

NM_005157.6

p.K356_K357ins0

c.1068_1070dupGAA