Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

8 papers

NM_007314.4

p.K930R

c.2789A>G

Surrounding Variants

1 paper

NM_007314.4

p.V931L

c.2791G>T

1 paper

NM_007314.4

p.V931L

c.2791G>C

2 papers

NM_007314.4

p.P932L

c.2795C>T

1 paper

NM_007314.4

p.H927H

c.2781C>T

1 paper

NM_007314.4

p.V933V

c.2799C>T

1 paper

NM_007314.4

p.I935V

c.2803A>G

1 paper

NM_007314.4

p.T938S

c.2812A>T

1 paper

NM_007314.4

p.T938S

c.2813C>G

1 paper

NM_007314.4

p.T942P

c.2824A>C

1 paper

NM_007314.4

p.A944P

c.2830G>C

1 paper

NM_007314.4

p.S915F

c.2744C>T

1 paper

NM_007314.4

p.P914R

c.2741C>G