Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_007314.4

p.T872R

c.2615C>G

Surrounding Variants

1 paper

NM_007314.4

p.P876S

c.2626C>T

1 paper

NM_007314.4

p.G867_D868insFs

c.2601_2602insC

1 paper

NM_007314.4

p.S866delFs

c.2597delG

1 paper

NM_007314.4

p.S866F

c.2597C>T

1 paper

NM_007314.4

p.S866insFs

c.2596_2597insG

1 paper

NM_007314.4

p.G880E

c.2639G>A

1 paper

NM_007314.4

p.R863K

c.2588G>A

2 papers

NM_007314.4

p.A859G

c.2576C>G

1 paper

NM_007314.4

p.P854L

c.2561C>T

1 paper

NM_007314.4

p.A850fs

c.2548_2549fs

1 paper

NM_007314.4

p.K849delFs

c.2547delT

1 paper

NM_007314.4

p.R898Q

c.2693G>A