Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_007314.4

p.K836fs

c.2506_2507fs

Surrounding Variants

2 papers

NM_007314.4

p.K836fs

c.2506_2507fs

2 papers

NM_007314.4

p.K836delFs

c.2508delT

1 paper

NM_007314.4

p.A829fs

c.2485_2486fs

1 paper

NM_007314.4

p.A829P

c.2485G>C

1 paper

NM_007314.4

p.P843L

c.2528C>T

1 paper

NM_007314.4

p.D827G

c.2480A>G

1 paper

NM_007314.4

p.V826V

c.2478G>C

1 paper

NM_007314.4

p.E824D

c.2472G>T

1 paper

NM_007314.4

p.E824D

c.2472G>C

1 paper

NM_007314.4

p.K849delFs

c.2547delT

1 paper

NM_007314.4

p.A850fs

c.2548_2549fs

1 paper

NM_007314.4

p.P854L

c.2561C>T