Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007314.4

p.S786P

c.2356T>C

Surrounding Variants

1 paper

NM_007314.4

p.M787V

c.2359A>G

1 paper

NM_007314.4

p.T784S

c.2350A>T

1 paper

NM_007314.4

p.S781L

c.2342C>T

1 paper

NM_007314.4

p.P779S

c.2335C>T

1 paper

NM_007314.4

p.Q794*

c.2380C>T

1 paper

NM_007314.4

p.A798S

c.2392G>T

1 paper

NM_007314.4

p.A798P

c.2392G>C

1 paper

NM_007314.4

p.A798V

c.2393C>T

2 papers

NM_007314.4

p.D773N

c.2317G>A

1 paper

NM_007314.4

p.M799L

c.2395A>T

1 paper

NM_007314.4

p.M799L

c.2395A>C

9 papers

NM_007314.4

p.T769S

c.2305A>T