Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007314.4

p.G742R

c.2224G>C

Surrounding Variants

1 paper

NM_007314.4

p.G742R

c.2224G>A

1 paper

NM_007314.4

p.A741delFs

c.2222_2223delAG

1 paper

NM_007314.4

p.G737_A741delFs

c.2211_2223del13

1 paper

NM_007314.4

p.A741A

c.2223T>G

1 paper

NM_007314.4

p.G742E

c.2225G>A

1 paper

NM_007314.4

p.A741del1

c.2221_2222delAGC

1 paper

NM_007314.4

p.G742G

c.2226G>A

2 papers

NM_007314.4

p.G743S

c.2227G>A

1 paper

NM_007314.4

p.G743fs

c.2227_2228fs

1 paper

NM_007314.4

p.G743delFs

c.2228delC

1 paper

NM_007314.4

p.G744R

c.2230G>C

1 paper

NM_007314.4

p.G744R

c.2230G>A