Varaico: Literature-Extracted Genetic Variants

ABL2

292 papers

RefSeq Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 doma...

Pfam Domains

SH3_1aa 113–159UCSCSH3 domain

SH2aa 173–248UCSCSH2 domain

PK_Tyr_Ser-Thraa 288–539UCSCProtein tyrosine and serine/threonine kinase

F_actin_bindaa 1082–1182UCSCF-actin binding

Gene Aliases

HGNC Name

ABL proto-oncogene 2, non-receptor tyrosine kinase

HGNC Previous Symbol

ABLL

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007314.4

p.L111P

c.332T>C

Surrounding Variants

1 paper

NM_007314.4

p.V113L

c.337G>C

1 paper

NM_007314.4

p.D108E

c.324C>G

1 paper

NM_007314.4

p.D108E

c.324C>A

1 paper

NM_007314.4

p.A114E

c.341C>A

1 paper

NM_007314.4

p.S107N

c.320G>A

1 paper

NM_007314.4

p.Y116F

c.347A>T

1 paper

NM_007314.4

p.A104V

c.311C>T

2 papers

NM_007314.4

p.G103R

c.307G>C

2 papers

NM_007314.4

p.G103R

c.307G>A

1 paper

NM_007314.4

p.D123N

c.367G>A

1 paper

NM_007314.4

p.E99Q

c.295G>C

1 paper

NM_007314.4

p.T125R

c.374C>G