Varaico: Literature-Extracted Genetic Variants

Gene:ACO2
Variant:p.G661R

ACO2

234 papers

RefSeq Summary

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the ...

Pfam Domains

Aconitaseaa 67–503UCSCAconitase family (aconitate hydratase)
Aconitase_Caa 582–712UCSCAconitase C-terminal domain

Gene Aliases

HGNC Name

aconitase 2

HGNC Alias Symbol

ACONM

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
15 papers
NM_001098.3
p.G661R
c.1981G>C
Surrounding Variants
16 papers
NM_001098.3
p.G661R
c.1981G>A
1 paper
NM_001098.3
p.G661V
c.1982G>T
1 paper
NM_001098.3
p.D662D
c.1986C>T
3 papers
NM_001098.3
p.E663*
c.1987G>T
3 papers
NM_001098.3
p.Y665insFs
c.1995dupC
1 paper
NM_001098.3
p.R656fs
c.1966_1967fs
3 papers
NM_001098.3
p.G666fs
c.1996_1997fs
7 papers
NM_001098.3
p.G666A
c.1997G>C
6 papers
NM_001098.3
p.E667K
c.1999G>A
1 paper
NM_001098.3
p.G668A
c.2003G>C
5 papers
NM_001098.3
p.S669L
c.2006C>T
3 papers
NM_001098.3
p.R671W
c.2011C>T
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."