acyl-CoA synthetase long chain family member 6

FACL6

KIAA0837

ACS2

LACS5

LACS2

fatty-acid-Coenzyme A ligase, long-chain 6

Long-chain-fatty-acid--CoA ligase 6

Arachidonate--CoA ligase

Long-chain acyl-CoA synthetase 6

LACS 6

The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011].

Varaico: Literature-Extracted Genetic Variants

ACSL6

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Previous Symbol