Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.E522G

c.1565A>G

Surrounding Variants

1 paper

NM_001110.4

p.S521P

c.1561T>C

1 paper

NM_001110.4

p.K523fs

c.1567_1568fs

4 papers

NM_001110.4

p.C524Y

c.1571G>A

1 paper

NM_001110.4

p.R525W

c.1573C>T

1 paper

NM_001110.4

p.S519S

c.1557A>C

1 paper

NM_001110.4

p.R525Q

c.1574G>A

1 paper

NM_001110.4

p.S519L

c.1556C>T

1 paper

NM_001110.4

p.S519T

c.1555T>A

1 paper

NM_001110.4

p.D526N

c.1576G>A

1 paper

NM_001110.4

p.K518R

c.1553A>G

1 paper

NM_001110.4

p.E522_R525del4

c.1564_1574del12

1 paper

NM_001110.4

p.D527N

c.1579G>A