Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.A315V

c.944C>T

Surrounding Variants

1 paper

NM_001110.4

p.H309R

c.926A>G

1 paper

NM_001110.4

p.N308I

c.923A>T

1 paper

NM_001110.4

p.D322insFs

c.965_966insC

1 paper

NM_001110.4

p.N308Y

c.922A>T

1 paper

NM_001110.4

p.E306K

c.916G>A

1 paper

NM_001110.4

p.D325insFs

c.973dupG

1 paper

NM_001110.4

p.V327I

c.979G>A

1 paper

NM_001110.4

p.G329D

c.986G>A

1 paper

NM_001110.4

p.K299M

c.896A>T

1 paper

NM_001110.4

p.K299R

c.896A>G

1 paper

NM_001110.4

p.W332G

c.994T>G

1 paper

NM_001110.4

p.V333F

c.997G>T