Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_001110.4

p.R291H

c.872G>A

Surrounding Variants

1 paper

NM_001110.4

p.R291C

c.871C>T

1 paper

NM_001110.4

p.F292I

c.874T>A

1 paper

NM_001110.4

p.F290S

c.869T>C

1 paper

NM_001110.4

p.P293A

c.877C>G

1 paper

NM_001110.4

p.N294S

c.881A>G

1 paper

NM_001110.4

p.N294T

c.881A>C

1 paper

NM_001110.4

p.I295V

c.883A>G

1 paper

NM_001110.4

p.T287R

c.860C>G

1 paper

NM_001110.4

p.T287P

c.859A>C

1 paper

NM_001110.4

p.P286L

c.857C>T

1 paper

NM_001110.4

p.P286S

c.856C>T

1 paper

NM_001110.4

p.V297M

c.889G>A