Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001110.4

p.A252V

c.755C>T

Surrounding Variants

1 paper

NM_001110.4

p.A252T

c.754G>A

2 papers

NM_001110.4

p.T255S

c.763A>T

6 papers

NM_001110.4

p.T255A

c.763A>G

1 paper

NM_001110.4

p.T255I

c.764C>T

1 paper

NM_001110.4

p.T255K

c.764C>A

2 papers

NM_001110.4

p.S248G

c.742A>G

1 paper

NM_001110.4

p.S247P

c.739T>C

1 paper

NM_001110.4

p.I246L

c.736A>T

1 paper

NM_001110.4

p.I246L

c.736A>C

1 paper

NM_001110.4

p.T259A

c.775A>G

1 paper

NM_001110.4

p.D261N

c.781G>A

1 paper

NM_001110.4

p.G264R

c.790G>C