Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001110.4

p.V190A

c.569T>C

Surrounding Variants

1 paper

NM_001110.4

p.V190I

c.568G>A

1 paper

NM_001110.4

p.E191K

c.571G>A

1 paper

NM_001110.4

p.E191G

c.572A>G

1 paper

NM_001110.4

p.G189fs

c.565_566fs

1 paper

NM_001110.4

p.E191D

c.573G>T

1 paper

NM_001110.4

p.E191D

c.573G>C

1 paper

NM_001110.4

p.E192fs

c.574_575fs

1 paper

NM_001110.4

p.T188S

c.563C>G

1 paper

NM_001110.4

p.T188N

c.563C>A

1 paper

NM_001110.4

p.E192insFs

c.575_576insCC

1 paper

NM_001110.4

p.T188_E192delFs

c.564_574del11

1 paper

NM_001110.4

p.T188S

c.562A>T