Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.Y185*

c.555C>G

Surrounding Variants

1 paper

NM_001110.4

p.Y185N

c.553T>A

1 paper

NM_001110.4

p.Q186R

c.557A>G

1 paper

NM_001110.4

p.Q186insFs

c.556dupC

1 paper

NM_001110.4

p.Q186_M187insFs

c.558_559insC

1 paper

NM_001110.4

p.M187L

c.559A>T

1 paper

NM_001110.4

p.M187L

c.559A>C

1 paper

NM_001110.4

p.M187I

c.561G>T

1 paper

NM_001110.4

p.M187I

c.561G>C

1 paper

NM_001110.4

p.M187I

c.561G>A

1 paper

NM_001110.4

p.T188S

c.562A>T

1 paper

NM_001110.4

p.T188S

c.563C>G

1 paper

NM_001110.4

p.T188N

c.563C>A