Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.S177A

c.529T>G

Surrounding Variants

1 paper

NM_001110.4

p.S177S

c.531A>G

1 paper

NM_001110.4

p.H176R

c.527A>G

1 paper

NM_001110.4

p.V178L

c.532G>T

1 paper

NM_001110.4

p.V178L

c.532G>C

2 papers

NM_001110.4

p.H176Y

c.526C>T

1 paper

NM_001110.4

p.A174_D175delFs

c.522_525del4

1 paper

NM_001110.4

p.D175G

c.524A>G

1 paper

NM_001110.4

p.D175N

c.523G>A

1 paper

NM_001110.4

p.C173Y

c.518G>A

40 papers

NM_001110.4

p.R181G

c.541A>G

1 paper

NM_001110.4

p.G172delFs

c.515delC

1 paper

NM_001110.4

p.G172V

c.515G>T