Varaico: Literature-Extracted Genetic Variants

ADAM10

266 papers

RefSeq Summary

Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many protein...

Pfam Domains

Reprolysin_2aa 239–446UCSCMetallo-peptidase family M12B Reprolysin-like

Disintegrinaa 466–546UCSCDisintegrin

ADAM10_Cys-richaa 591–646UCSCADAM10, cysteine-rich domain

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 10

HGNC Alias Symbols

kuz; MADM; HsT18717; CD156C

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_001110.4

p.D146E

c.438C>G

Surrounding Variants

1 paper

NM_001110.4

p.D146E

c.438C>A

1 paper

NM_001110.4

p.D146A

c.437A>C

1 paper

NM_001110.4

p.R147Q

c.440G>A

1 paper

NM_001110.4

p.I144V

c.430A>G

1 paper

NM_001110.4

p.Y143*

c.429T>G

1 paper

NM_001110.4

p.Y143*

c.429T>A

1 paper

NM_001110.4

p.R142fs

c.424_425fs

1 paper

NM_001110.4

p.P150delFs

c.448_449delGG

1 paper

NM_001110.4

p.R142insFs

c.425_426ins5

1 paper

NM_001110.4

p.R142insFs

c.424_425ins5

1 paper

NM_001110.4

p.H152insFs

c.456dupC

1 paper

NM_001110.4

p.H152delFs

c.456delG