Varaico: Literature-Extracted Genetic Variants

ADAM21

97 papers

RefSeq Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and ha...

Pfam Domains

Pep_M12B_propepaa 41–116UCSCReprolysin family propeptide

Reprolysinaa 208–398UCSCReprolysin (M12B) family zinc metalloprotease

Disintegrinaa 415–487UCSCDisintegrin

ADAM_CRaa 492–605UCSCADAM cysteine-rich

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 21

HGNC Alias Symbol

ADAM31

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003813.4

p.P459S

c.1375C>T

Surrounding Variants

1 paper

NM_003813.4

p.F457L

c.1371C>A

1 paper

NM_003813.4

p.F457L

c.1371C>G

1 paper

NM_003813.4

p.F457L

c.1369T>C

1 paper

NM_003813.4

p.K456K

c.1368G>A

1 paper

NM_003813.4

p.H482R

c.1445A>G

1 paper

NM_003813.4

p.H482L

c.1445A>T

2 papers

NM_003813.4

p.Q483Q

c.1449G>A

1 paper

NM_003813.4

p.E429Q

c.1285G>C

1 paper

NM_003813.4

p.I494fs

c.1480_1481fs

1 paper

NM_003813.4

p.C420R

c.1258T>C

1 paper

NM_003813.4

p.A500S

c.1498G>T

1 paper

NM_003813.4

p.G412_V413del1

c.1236_1238delTGT