Varaico: Literature-Extracted Genetic Variants

ADAM21

97 papers

RefSeq Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and ha...

Pfam Domains

Pep_M12B_propepaa 41–116UCSCReprolysin family propeptide

Reprolysinaa 208–398UCSCReprolysin (M12B) family zinc metalloprotease

Disintegrinaa 415–487UCSCDisintegrin

ADAM_CRaa 492–605UCSCADAM cysteine-rich

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 21

HGNC Alias Symbol

ADAM31

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003813.4

p.H632fs

c.1894_1895fs

Surrounding Variants

1 paper

NM_003813.4

p.H632delFs

c.1895_1896delAT

1 paper

NM_003813.4

p.V629A

c.1886T>C

1 paper

NM_003813.4

p.E637*

c.1909G>T

1 paper

NM_003813.4

p.V625L

c.1873G>C

1 paper

NM_003813.4

p.C624W

c.1872T>G

1 paper

NM_003813.4

p.C619*

c.1857C>A

1 paper

NM_003813.4

p.K617M

c.1850A>T

1 paper

NM_003813.4

p.Y655*

c.1965T>A

1 paper

NM_003813.4

p.Y655*

c.1965T>G

1 paper

NM_003813.4

p.Y661fs

c.1981_1982fs

1 paper

NM_003813.4

p.Y661C

c.1982A>G

1 paper

NM_003813.4

p.D594N

c.1780G>A