Varaico: Literature-Extracted Genetic Variants

ADAM7

82 papers

RefSeq Summary

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein la...

Pfam Domains

Pep_M12B_propepaa 27–114UCSCReprolysin family propeptide

Reprolysinaa 199–394UCSCReprolysin (M12B) family zinc metalloprotease

Disintegrinaa 411–483UCSCDisintegrin

ADAM_CRaa 488–602UCSCADAM cysteine-rich

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 7

HGNC Alias Symbols

GP-83; EAPI

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003817.4

p.A330S

c.988G>T

Surrounding Variants

1 paper

NM_003817.4

p.D321Y

c.961G>T

1 paper

NM_003817.4

p.L341F

c.1021C>T

1 paper

NM_003817.4

p.M343K

c.1028T>A

1 paper

NM_003817.4

p.Q344Q

c.1032G>A

1 paper

NM_003817.4

p.P349P

c.1047A>G

1 paper

NM_003817.4

p.C357*

c.1071C>A

3 papers

NM_003817.4

p.V358M

c.1072G>A

1 paper

NM_003817.4

p.M359I

c.1077G>A

1 paper

NM_003817.4

p.M359I

c.1077G>C

1 paper

NM_003817.4

p.M359I

c.1077G>T

1 paper

NM_003817.4

p.S364R

c.1090A>C

1 paper

NM_003817.4

p.S364R

c.1092C>A