Varaico: Literature-Extracted Genetic Variants

ADAM7

82 papers

RefSeq Summary

This gene encodes a member of the ADAMs family of zinc proteases. These transmembrane proteins play roles in multiple processes including cell signaling, adhesion and migration. The encoded protein la...

Pfam Domains

Pep_M12B_propepaa 27–114UCSCReprolysin family propeptide

Reprolysinaa 199–394UCSCReprolysin (M12B) family zinc metalloprotease

Disintegrinaa 411–483UCSCDisintegrin

ADAM_CRaa 488–602UCSCADAM cysteine-rich

Gene Aliases

HGNC Name

ADAM metallopeptidase domain 7

HGNC Alias Symbols

GP-83; EAPI

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003817.4

p.G537V

c.1610G>T

Surrounding Variants

1 paper

NM_003817.4

p.N534K

c.1602T>A

2 papers

NM_003817.4

p.G533E

c.1598G>A

1 paper

NM_003817.4

p.T531I

c.1592C>T

2 papers

NM_003817.4

p.Y527H

c.1579T>C

1 paper

NM_003817.4

p.C549F

c.1646G>T

1 paper

NM_003817.4

p.D524V

c.1571A>T

1 paper

NM_003817.4

p.C511C

c.1533C>T

1 paper

NM_003817.4

p.P505S

c.1513C>T

1 paper

NM_003817.4

p.G502E

c.1505G>A

1 paper

NM_003817.4

p.M501I

c.1503G>A

1 paper

NM_003817.4

p.M501I

c.1503G>C

1 paper

NM_003817.4

p.M501I

c.1503G>T