Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_030957.4

p.H1101Q

c.3303T>G

Surrounding Variants

5 papers

NM_030957.4

p.H1101Q

c.3303T>A

1 paper

NM_030957.4

p.Q1085delFs

c.3254_3255delCT

1 paper

NM_030957.4

p.G1065S

c.3193G>A

1 paper

NM_030957.4

p.C1041G

c.3121T>G

1 paper

NM_030957.4

p.T1034T

c.3102G>A

1 paper

NM_030957.4

p.R1026C

c.3076C>T

1 paper

NM_030957.4

p.C1015F

c.3044G>T

1 paper

NM_030957.4

p.E1011*

c.3031G>T

1 paper

NM_030957.4

p.V1008M

c.3022G>A

1 paper

NM_030957.4

p.A983V

c.2948C>T

1 paper

NM_030957.4

p.R977_T979del0

c.2930_2935del6

1 paper

NM_030957.4

p.P962T

c.2884C>A