Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030957.4

p.F815L

c.2443T>C

Surrounding Variants

1 paper

NM_030957.4

p.F815L

c.2445C>G

1 paper

NM_030957.4

p.F815L

c.2445C>A

1 paper

NM_030957.4

p.A820T

c.2458G>A

1 paper

NM_030957.4

p.L808R

c.2423T>G

1 paper

NM_030957.4

p.P825S

c.2473C>T

1 paper

NM_030957.4

p.L803L

c.2409G>A

2 papers

NM_030957.4

p.W829R

c.2485T>C

2 papers

NM_030957.4

p.W829R

c.2485T>A

1 paper

NM_030957.4

p.C837S

c.2509T>A

1 paper

NM_030957.4

p.C837S

c.2510G>C

1 paper

NM_030957.4

p.G792_M801delFs

c.2376_2401del26

1 paper

NM_030957.4

p.L798V

c.2392C>G