Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030957.4

p.D349Y

c.1045G>T

Surrounding Variants

1 paper

NM_030957.4

p.Y348C

c.1043A>G

1 paper

NM_030957.4

p.R347R

c.1041C>G

1 paper

NM_030957.4

p.N355K

c.1065C>G

1 paper

NM_030957.4

p.N355K

c.1065C>A

1 paper

NM_030957.4

p.G362Splc

c.1085-47A>G

1 paper

NM_030957.4

p.G367G

c.1101C>T

1 paper

NM_030957.4

p.E371Q

c.1111G>C

1 paper

NM_030957.4

p.R372_E373insGT

c.1114_1118ins6

1 paper

NM_030957.4

p.R372S

c.1114C>A

1 paper

NM_030957.4

p.P365_E371del0

c.1095_1112del18

1 paper

NM_030957.4

p.S375I

c.1124G>T

6 papers

NM_030957.4

p.A387T

c.1159G>A