Varaico: Literature-Extracted Genetic Variants

ADAMTS10

170 papers

RefSeq Summary

This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes contain...

Pfam Domains

Pep_M12B_propepaa 40–129UCSCReprolysin family propeptide

Reprolysinaa 239–457UCSCReprolysin (M12B) family zinc metalloprotease

ADAMTS_CR_2aa 469–537UCSCADAMTS cysteine-rich domain 2

TSP_1aa 551–601UCSCThrombospondin type 1 domain

ADAMTS_CR_3aa 604–705UCSCADAMTS cysteine-rich domain

ADAMTS_spacer1aa 707–818UCSCADAM-TS Spacer 1

Gene Aliases

HGNC Name

ADAM metallopeptidase with thrombospondin type 1 motif 10

HGNC Alias Symbol

ADAM-TS10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_030957.4

p.M1R

c.2T>G

Surrounding Variants

1 paper

NM_030957.4

p.M1delins

c.3delinsTTTTAGATCCATATTTTAG

1 paper

NM_030957.4

p.A2T

c.4G>A

1 paper

NM_030957.4

p.R9H

c.26G>A

3 papers

NM_030957.4

p.L14Q

c.41T>A

1 paper

NM_030957.4

p.F20V

c.58T>G

1 paper

NM_030957.4

p.V22F

c.64G>T

12 papers

NM_030957.4

p.A25T

c.73G>A

1 paper

NM_030957.4

p.R27G

c.79C>G

1 paper

NM_030957.4

p.S28insFs

c.82dupT

1 paper

NM_030957.4

p.D30E

c.90T>G

1 paper

NM_030957.4

p.D30E

c.90T>A

1 paper

NM_030957.4

p.E31G

c.92A>G