Varaico: Literature-Extracted Genetic Variants

ADGRA3

125 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila d...

Pfam Domains

LRR_8aa 81–141UCSCLeucine rich repeat

LRR_8aa 129–186UCSCLeucine rich repeat

GAIN_ADGRA3aa 418–524UCSCADGRA3-like, GAIN domain

GPSaa 699–743UCSCGPCR proteolysis site, GPS, motif

7tm_2aa 757–1043UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor A3

HGNC Previous Symbol

GPR125

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_145290.4

p.S835C

c.2504C>G

Surrounding Variants

3 papers

NM_145290.4

p.K852N

c.2556A>T

3 papers

NM_145290.4

p.K852N

c.2556A>C

1 paper

NM_145290.4

p.Q862P

c.2585A>C

1 paper

NM_145290.4

p.P864S

c.2590C>T

1 paper

NM_145290.4

p.M874V

c.2620A>G

1 paper

NM_145290.4

p.I886_I887del1

c.2658_2660delATG

1 paper

NM_145290.4

p.S902G

c.2704A>G

1 paper

NM_145290.4

p.Y921C

c.2762A>G

2 papers

NM_145290.4

p.F926V

c.2776T>G

1 paper

NM_145290.4

p.H945Q

c.2835C>G

1 paper

NM_145290.4

p.H945Q

c.2835C>A

1 paper

NM_145290.4

p.R948H

c.2843G>A