Varaico: Literature-Extracted Genetic Variants

ADGRA3

125 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila d...

Pfam Domains

LRR_8aa 81–141UCSCLeucine rich repeat

LRR_8aa 129–186UCSCLeucine rich repeat

GAIN_ADGRA3aa 418–524UCSCADGRA3-like, GAIN domain

GPSaa 699–743UCSCGPCR proteolysis site, GPS, motif

7tm_2aa 757–1043UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor A3

HGNC Previous Symbol

GPR125

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145290.4

p.S736A

c.2206T>G

Surrounding Variants

1 paper

NM_145290.4

p.T731M

c.2192C>T

1 paper

NM_145290.4

p.A741G

c.2222C>G

1 paper

NM_145290.4

p.S725*

c.2174C>G

1 paper

NM_145290.4

p.S725*

c.2174C>A

1 paper

NM_145290.4

p.D707N

c.2119G>A

2 papers

NM_145290.4

p.A697_A699del3

c.2089_2096del9

2 papers

NM_145290.4

p.R691H

c.2072G>A

1 paper

NM_145290.4

p.L690L

c.2070G>C

1 paper

NM_145290.4

p.V686A

c.2057T>C

1 paper

NM_145290.4

p.V677V

c.2031G>A

1 paper

NM_145290.4

p.I674T

c.2021T>C

3 papers

NM_145290.4

p.L671L

c.2013C>T