Varaico: Literature-Extracted Genetic Variants

ADGRA3

125 papers

RefSeq Summary

This gene encodes a member of the G protein-coupled receptor superfamily. This membrane protein may play a role in tumor angiogenesis through its interaction with the human homolog of the Drosophila d...

Pfam Domains

LRR_8aa 81–141UCSCLeucine rich repeat

LRR_8aa 129–186UCSCLeucine rich repeat

GAIN_ADGRA3aa 418–524UCSCADGRA3-like, GAIN domain

GPSaa 699–743UCSCGPCR proteolysis site, GPS, motif

7tm_2aa 757–1043UCSC7 transmembrane receptor (Secretin family)

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor A3

HGNC Previous Symbol

GPR125

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_145290.4

p.I493T

c.1478T>C

Surrounding Variants

1 paper

NM_145290.4

p.V500I

c.1498G>A

1 paper

NM_145290.4

p.I514I

c.1542T>C

1 paper

NM_145290.4

p.L518F

c.1552C>T

1 paper

NM_145290.4

p.R520C

c.1558C>T

1 paper

NM_145290.4

p.A522D

c.1565C>A

1 paper

NM_145290.4

p.A527V

c.1580C>T

1 paper

NM_145290.4

p.G528S

c.1582G>A

1 paper

NM_145290.4

p.T553T

c.1659G>A

1 paper

NM_145290.4

p.R568H

c.1703G>A

2 papers

NM_145290.4

p.S572L

c.1715C>T

1 paper

NM_145290.4

p.T596T

c.1788A>G