Varaico: Literature-Extracted Genetic Variants

ADGRB2

137 papers

RefSeq Summary

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature pep...

Pfam Domains

AGRB_Naa 38–230UCSCAdhesion GPCR B N-terminal region

TSP_1aa 313–361UCSCThrombospondin type 1 domain

TSP_1aa 368–416UCSCThrombospondin type 1 domain

TSP_1aa 423–471UCSCThrombospondin type 1 domain

TSP_1aa 479–527UCSCThrombospondin type 1 domain

GAINaa 596–706UCSCAGRL2-4 GAIN subdomain A

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor B2

HGNC Previous Symbol

BAI2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 191 variants

4 papers

NM_001364857.2

p.P175P

c.525C>T

4 papers

NM_001364857.2

p.P853L

c.2558C>T

4 papers

NM_001364857.2

p.R1465W

c.4393C>T

3 papers

NM_001364857.2

p.S63L

c.188C>T

2 papers

NM_001364857.2

p.P287L

c.860C>T

2 papers

NM_001364857.2

p.A548V

c.1643C>T

2 papers

NM_001364857.2

p.A549G

c.1646C>G

2 papers

NM_001364857.2

p.R696C

c.2086C>T

2 papers

NM_001364857.2

p.G868A

c.2603G>C

2 papers

NM_001364857.2

p.R1028P

c.3083G>C

2 papers

NM_001364857.2

p.V1052M

c.3154G>A

2 papers

NM_001364857.2

p.V1086I

c.3256G>A