Varaico: Literature-Extracted Genetic Variants

ADGRB2

137 papers

RefSeq Summary

This gene encodes a a seven-span transmembrane protein that is thought to be a member of the secretin receptor family. The encoded protein is a brain-specific inhibitor of angiogenesis. The mature pep...

Pfam Domains

AGRB_Naa 38–230UCSCAdhesion GPCR B N-terminal region

TSP_1aa 313–361UCSCThrombospondin type 1 domain

TSP_1aa 368–416UCSCThrombospondin type 1 domain

TSP_1aa 423–471UCSCThrombospondin type 1 domain

TSP_1aa 479–527UCSCThrombospondin type 1 domain

GAINaa 596–706UCSCAGRL2-4 GAIN subdomain A

Gene Aliases

HGNC Name

adhesion G protein-coupled receptor B2

HGNC Previous Symbol

BAI2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_001364857.2

p.P853L

c.2558C>T

Surrounding Variants

1 paper

NM_001364857.2

p.P856T

c.2566C>A

1 paper

NM_001364857.2

p.P849delFs

c.2546delG

1 paper

NM_001364857.2

p.I858F

c.2572A>T

2 papers

NM_001364857.2

p.G868A

c.2603G>C

1 paper

NM_001364857.2

p.T869A

c.2605A>G

1 paper

NM_001364857.2

p.T870T

c.2610G>A

1 paper

NM_001364857.2

p.H873H

c.2619T>C

1 paper

NM_001364857.2

p.A875V

c.2624C>T

1 paper

NM_001364857.2

p.R822H

c.2465G>A

1 paper

NM_001364857.2

p.V819L

c.2455G>T

1 paper

NM_001364857.2

p.V819L

c.2455G>C

1 paper

NM_001364857.2

p.D807Y

c.2419G>T